Figure 2b. Scatterplots show distributions of the low-risk cases (
) and the BRCA1 and BRCA2 mutation carriers (
) in the entire group (172 cases) in terms of (a) skewness versus coarseness and (b) coarseness versus contrast. The two-dimensional projection line from LDA corresponds to the line that yields the best (or maximum) separation between the BRCA mutation carriers and the low-risk cases in the corresponding two-dimensional feature space. As indicated by the diagonal line, the mutation carriers tended to have more dense breast tissue, with coarser and lower contrast texture patterns on their mammograms, than did the low-risk women.