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Radiology, Vol 122, 377-378, Copyright © 1977 by Radiological Society of North America

ARTICLES

Computed tomographic appearance of methotrexate-induced necrotizing leukoencephalopathy

JE Bjorgen and LH Gold

A case of methotrexate-induced brain damage is presented. Computed tomography (CT) demonstrated a high-density mass lesion with a low- density area in the white matter which pathologically represented a large area of acute necrotizing cerebritis. CT appearance was indistinguishable from brain abscess.


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 Arch NeurolHome page
R. J. Packer, R. A. Zimmerman, J. Rosenstock, L. B. Rorke, D. G. Norris, and P. H. Berman
Focal Encephalopathy Following Methotrexate Therapy: Administration Via a Misplaced Intraventricular Catheter
Arch Neurol, July 1, 1981; 38(7): 450 - 452.
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