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Radiology, Vol 122, 517-519, Copyright © 1977 by Radiological Society of North America

ARTICLES

A radiographic and histologic study of fracture healing in osteopetrotic rats

CJ Schmidt, SC Marks Jr, CA Jordan and LE Hawes

Repair of tibial fractures in osteopetrotic rats was delayed in comparison to that of normal littermates, due to reduced remodeling. Reduced bone resorption, known to be the cause of the disease in this mutation, is expressed in both skeletal development and fracture repair. The possible implications for human juvenile osteopetrosis are discussed.




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RADIOLOGY RADIOGRAPHICS RSNA JOURNALS ONLINE
Copyright © 1977 by the Radiological Society of North America.