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Radiology, Vol 124, 813-814, Copyright © 1977 by Radiological Society of North America

ARTICLES

Radiation necrosis of the scalp: a complication of cranial irradiation and methotrexate

YH Kim, MS Aye and JV Fayos

A case of childhood leukemia with a severe skin reaction following a course of medium-dose cranial irradiation and intrathecal methotrexate is presented. Necrosis of the scalp of partial to full thickness resulted. The authors believe potentiation of the radiation reaction by methotrexate was the probable cause.




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