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Radiology, Vol 158, 327-332, Copyright © 1986 by Radiological Society of North America

ARTICLES

Liver metastases: detection by phase-contrast MR imaging

DD Stark, J Wittenberg, MS Middleton and JT Ferrucci Jr

Forty patients with biopsy-proved metastatic liver cancers were studied by magnetic resonance (MR) imaging using one or more conventional (in- phase) pulse sequences and a corresponding phase-contrast (opposed- phase) pulse sequence. Pulse-sequence performance was quantitated by measuring signal-difference-to-noise (SD/N) ratios between cancerous tissue and liver. The SD/N performance of T2-weighted spin-echo (SE) pulse sequences improved when used with the phase-contrast technique. SE 2,000/30 opposed-phase images showed improved (P less than .001) SD/N in 72% of patients over in-phase images. The SD/N of T1-weighted SE or inversion recovery pulse sequences deteriorated when used with the phase-contrast technique. Changes in measured SD/N correlated well with image appearance and actual lesion detectability in individual cases. Phase-contrast imaging should be employed routinely when T2- weighted SE pulse sequences are relied on to detect liver cancer.


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