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Radiology, Vol 180, 333-336, Copyright © 1991 by Radiological Society of North America

ARTICLES

Small hepatocellular carcinoma treated with percutaneous ethanol injection: MR imaging findings

S Sironi, T Livraghi and A DelMaschio
Department of Radiology, Scientific Institute San Raffaele, University Hospital, Milan, Italy.

Fifty-seven magnetic resonance (MR) imaging examinations were obtained at 0.5 T in 19 patients before and after percutaneous ethanol injection (PEI) for 23 hepatocellular carcinoma (HCC) lesions less than 3.5 cm in diameter. Seventeen patients also underwent MR imaging 6 months after completion of therapy. In 11 patients, computed tomography was performed before and after treatment. After PEI, fine-needle biopsy specimens were obtained in all cases. Before treatment, HCC lesions had low signal intensity on T1-weighted images in 13 cases, had the same signal intensity as normal liver parenchyma in six, and had high signal intensity in four; all 23 tumors had high signal intensity on T2- weighted images. After treatment and at 6-month follow-up, all 21 lesions that contained no malignant cells at fine-needle biopsy had high signal intensity on T1-weighted images and had low signal intensity on T2-weighted images. The remaining two HCC lesions in which tumor necrosis was not achieved with PEI displayed a different MR pattern, since the residual neoplastic tissue showed no change in signal intensity on either T1- or T2-weighted images. The authors conclude that MR imaging may be useful for evaluating the effectiveness of PEI in achieving tumor regression.


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A. Dimitrakopoulou-Strauss, L. G. Strauss, F. Gutzler, G. Irngartinger, G. Kontaxakis, D. K. Kim, F. Oberdorfer, and G. van Kaick
Pharmacokinetic Imaging of 11C Ethanol with PET in Eight Patients with Hepatocellular Carcinomas Who Were Scheduled for Treatment with Percutaneous Ethanol Injection
Radiology, June 1, 1999; 211(3): 681 - 686.
[Abstract] [Full Text]


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