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Radiology, Vol 189, 65-68, Copyright © 1993 by Radiological Society of North America


ARTICLES

Generation of x rays for medical imaging by high-power lasers: preliminary results

K Herrlin, G Svahn, C Olsson, H Pettersson, C Tillman, A Persson, CG Wahlstrom and S Svanberg
Department of Radiology, University Hospital, Lund, Sweden.

PURPOSE: To evaluate the use of x-ray imaging performed with a high- power laser system in biologic and medical studies. MATERIALS AND METHODS: A compact terawatt laser system based on chirped pulse amplification in titanium-doped sapphire was used. X rays were generated by irradiating a high-atomic-number target (tantalum). RESULTS: When photons with an energy below 10 keV were removed with use of 3 mm of aluminum, the half-value layer in aluminum for the remaining x rays was approximately 10 mm. The x-ray source allowed performance of biologic magnification radiography. Star-pattern tests indicated an equivalent focal spot size of less than 60 microns. Exposures of a single pulse could be obtained. The duration of a single x-ray pulse was estimated to be of the order of picoseconds. CONCLUSION: With use of subpicosecond laser pulses, x-ray generation can occur with a smaller equivalent focal spot size than with conventional x-ray sources.


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C. Tillman, G. Grafström, A.-C. Jonsson, B.-A. Jönsson, I. Mercer, S. Mattsson, S.-E. Strand, and S. Svanberg
Survival of Mammalian Cells Exposed to Ultrahigh Dose Rates from a Laser-produced Plasma X-ray Source
Radiology, December 1, 1999; 213(3): 860 - 865.
[Abstract] [Full Text]




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