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Radiology, Vol 190, 727-736, Copyright © 1994 by Radiological Society of North America

ARTICLES

MR imaging of the liver: breath-hold T1-weighted MP-GRE compared with conventional T2-weighted SE imaging--lesion detection, localization, and characterization

EE de Lange, JP Mugler 3rd, JE Bosworth, GA DeAngelis, SB Gay, NS Hurt, SS Berr, JM Rosenblatt, LW Merickel and EK Harris
Department of Radiology, University of Virginia Health Sciences Center, Charlottesville 22908.

PURPOSE: To compare breath-hold T1-weighted magnetization-prepared gradient-echo (MP-GRE) imaging with conventional T2-weighted spin-echo (SE) imaging in evaluation of focal liver disease. MATERIALS AND METHODS: Images of 68 patients evaluated for focal liver disease were reviewed. Five sets of images were analyzed: axial, sagittal, and coronal breath-hold T1-weighted MP-GRE images, axial T2-weighted SE images, and a compilation of axial, sagittal, and coronal (three-plane) T1-weighted MP-GRE images. Lesion signal intensity (SI) and signal difference-to-noise (SD/N) ratios were calculated. RESULTS: Lesions were detected, localized, and characterize more accurately (P < .05- .001) and with greater confidence on three-plane T1-weighted MP-GRE images than on almost all single-plane images. Mean SI ratios of nonsolid and solid lesions on MP-GRE and SE images were significantly different at all lesion sizes; mean SD/N ratio was significantly different only for large lesions. CONCLUSION: Lesion detection, localization, and characterization can be accurately and confidently performed with three-plane T1-weighted MP-GRE breath-hold imaging, potentially obviating conventional T2-weighted SE imaging.


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