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Radiology, Vol 192, 393-399, Copyright © 1994 by Radiological Society of North America


ARTICLES

Hypervascular malignant liver lesions: comparison of various MR imaging pulse sequences and dynamic CT

RE Larson, RC Semelka, AS Bagley, PL Molina, ED Brown and JK Lee
Department of Radiology, University of North Carolina, Chapel Hill 27514.

PURPOSE: To compare the appearance of hypervascular liver lesions on gadolinium-enhanced fast low-angle shot (FLASH) imaging with T2- weighted fat-suppressed spin-echo imaging, dynamic nonequilibrium-phase FLASH imaging, and dynamic nonequilibrium-phase iodine-enhanced computed tomography (CT) and to characterize the appearance of lesions on serial postgadolinium FLASH images. MATERIALS AND METHODS: Twenty- nine patients with hypervascular malignant liver lesions were examined with dynamic contrast-enhanced CT and magnetic resonance (MR) imaging within a 1-month interval. MR sequences included T2-weighted fat- suppression, precontrast FLASH, and postgadolinium FLASH at 1 second (sinusoid phase), 45 seconds (nonequilibrium phase), and 10 minutes. RESULTS: More than five lesions were detected in 12 patients with CT, 15 patients with T2-weighted fat-suppression imaging, 16 with sinusoid- phase FLASH imaging, and 11 with nonequilibrium-phase FLASH imaging. In six patients, a statistically significant (P = .03) increase in the number of lesions detected, by category, was observed on sinusoid-phase FLASH images compared with CT images. CONCLUSION: Sinusoid-phase FLASH imaging is superior to nonequilibrium-phase imaging with MR or CT for the demonstration of hypervascular malignant lesions.


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