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Radiology, Vol 193, 665-669, Copyright © 1994 by Radiological Society of North America

ARTICLES

Hepatic tumors: detection and characterization at 1-T MR imaging enhanced with AMI-25

A Denys, L Arrive, V Servois, B Dubray, D Najmark, A Sibert and Y Menu
Department of Radiology, Hopital Beaujon, Clichy, France.

PURPOSE: To evaluate the ability of magnetic resonance (MR) imaging enhanced with AMI-25 to depict and characterize hepatic tumors. MATERIALS AND METHODS: Sixty-four patients (41 men and 23 women, aged 24-65 years [mean, 55 years]) underwent 1-T MR imaging: 22 had metastatic disease; 10, hepatocellular carcinoma; seven, hemangioma; three, focal nodular hyperplasia; three, gallbladder adenocarcinoma; two, lymphoma; one, adenoma; and 16, no tumor. Pre- and postcontrast images (alone and in combination) were analyzed by three independent radiologists. Receiver operating characteristic curves were constructed to compare tumor characterization. RESULTS: Signal intensity was decreased in all benign tumors but not in malignant tumors. The number of tumors depicted (nonenhanced images, 657 tumors; enhanced, 753; and combined, 760) was not statistically different. Receiver operating characteristic curves did not show improved characterization with AMI- 25. CONCLUSION: AMI-25 does not improve depiction of hepatic tumors. Although characterization of hepatic tumors was not improved with AMI- 25, uptake of AMI-25 seems specific for hepatic tumors at MR imaging.


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