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Radiology, Vol 195, 125-130, Copyright © 1995 by Radiological Society of North America

ARTICLES

Fatty metamorphosis of hepatocellular carcinoma: detection with chemical shift gradient-echo MR imaging

J Martin, M Sentis, A Zidan, L Donoso, J Puig, J Falco and R Bella
Unitat de Diagnostic per la Imatge d'Alta Tecnologia (UDIAT), Barcelona, Spain.

PURPOSE: To assess the value of chemical shift gradient-echo (GRE) magnetic resonance (MR) imaging with the fast low-angle shot (FLASH) technique to detect fatty metamorphosis in hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Sixty-three cirrhotic patients with 69 HCCs underwent MR imaging at 1.0 T with chemical shift GRE technique. Both opposed-phase and in-phase FLASH imaging with breath holding was performed, and the percentage variation in signal intensity of the nodules between the two images was calculated. RESULTS: Chemical shift GRE imaging depicted fat in 10 HCCs (14%). In these cases, the percentage variation in signal intensity increased notably and was 88.6%-369.3% (mean, 174.7%), which indicated fatty content (sensitivity, 100%; specificity, 100% when compared with fine-needle aspiration cytology). In the remaining 59 nodules, the percentage of signal intensity variation ranged from 12.7% to -19.1% (mean, -4.0%). CONCLUSION: Chemical shift GRE MR imaging can be used to detect fatty metamorphosis in HCC.




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Copyright © 1995 by the Radiological Society of North America.