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(Radiology. 1999;211:865-869.)
© RSNA, 1999


Technical Developments

Pulmonary MR Angiography with Ultrasmall Superparamagnetic Iron Oxide Particles as a Blood Pool Agent and a Navigator Echo for Respiratory Gating: Pilot Study1

K. Håkan Ahlström, MD, PhD, Lars O. Johansson, Johanne B. Rodenburg, PhD, A. Sgrimur Ragnarsson, MD, Per Åkeson and Arve Börseth, MSc

1 From the Department of Radiology, Uppsala University, Sjukhusvagen 5-11 Akademiska Sjukhuset, 751 85 Uppsala, Sweden (K.H.A., L.O.J.); Philips Medical Systems, Best, the Netherlands (J.B.R.); the Department of Radiology, Örebro Medical Center Hospital, Örebro, Sweden (A.S.R.); and Nycomed Amersham Imaging, Oslo, Norway (P.A., A.B.). Received April 7, 1998; revision requested June 29; revision received September 8; accepted December 9. Supported in part by a grant from Nycomed Amersham Imaging. Address reprint requests to K.H.A.

In nine healthy adult volunteers, pulmonary magnetic resonance angiography was performed with the blood pool agent NC100150 Injection combined with respiratory gating with a navigator echo. With increasing doses of the contrast agent, higher signal intensities and vessel branch order visualization were achieved. No motion artifacts were seen. The blood pool agent NC100150 Injection in combination with respiratory navigator gating permitted acquisition of high-quality MR angiograms of the pulmonary vasculature during continuous breathing.

Index terms: Embolism, pulmonary, 60.72 • Iron • Lung, MR, 60.121412, 60.12142, 60.12143 • Magnetic resonance (MR), contrast enhancement, 60.121412, 60.12142, 60.12143 • Magnetic resonance (MR), maximum intensity projection, 60.12149 • Magnetic resonance (MR), technology, 60.121412, 60.12142, 60.12143 • Magnetic resonance (MR), vascular studies, 60.121412, 60.12142, 60.12143




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