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Gadolinium-based Contrast Agents as an Alternative at Vena Cavography in Patients with Renal Insufficiency—Early Experience¹

¹ From the Division of Vascular Radiology (J.A.K., S.C.G., A.C.W.) and the Department of Medicine, Division of Nephrology (H.B.), Harvard Medical School, Massachusetts General Hospital, GRB 290, 55 Fruit St, Boston, MA 02114. Received April 30, 1998; revision requested July 6; revision received August 18; accepted December 15. Address reprint requests to J.A.K. (e-mail: kaufmanfamily@sprintmail.com).

The authors reviewed results of digital subtraction vena cavography with a gadolinium-based contrast agent in 14 patients with serum creatinine levels greater than or equal to 1.5 mg/dL (133 µmol/L). All cavograms were diagnostic. In 11 patients, there was no impairment of renal function. In three patients, a rise in serum creatinine level of greater than or equal to 0.5 mg/dL (44 µmol/L) was attributable to concurrent medical problems. Gadolinium-based contrast agents may be suitable for digital subtraction vena cavography in patients with renal insufficiency.

Index terms: Angiography, contrast media, 566.1245, 80.1248, 982.1245 • Venae cavae, angiography, 566.1245, 80.1248, 982.1245 • Venography, 566.1245, 80.1248, 982.1245

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