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Experimental Studies |
1 From the Hemodynamics and Cardiovascular Mechanics Laboratory, (P.H.R., H.B., A.F.) and the Departments of Radiology (A.B.C., G.M., J.M.B.) and Vascular Surgery (C.V., P.P.), Faculte de Medicine, 27 boulevard Jean-Moulin, F-13385 Marseille 5, France. Received March 24, 1998; revision requested June 17; final revision received December 30; accepted March 23, 1999. Address reprint requests to P.H.R. (e-mail: lab.hmcv@medecine.univ-mrs.fr).
PURPOSE: To compare the hemodynamics and wall mechanics of swine iliac arteries after placement of six types of stent.
MATERIALS AND METHODS: Stents were placed in the iliac artery of 18 pigs (three pigs each underwent placement with one of six types of stent); 16 untreated pigs served as control animals. Iliac arterial hemodynamics and wall mechanics were measured 4 days after placement.
RESULTS: Four stents (Palmaz-Schatz, Cordis, Warren, NJ; and Strecker, Cragg, and Symphony, Boston Scientific/Vascular, Natick, Mass) caused decreased pulsatile flow rate in the treated and contralateral iliac arteries; one (Memotherm; Bard, Covington, Ga) caused increased flow pulsatility; and one (Wallstent; Schneider, Plymouth, Minn) had no effect. No compliance mismatching was noted for the Cragg, Symphony, and Memotherm stents, whereas a decrease in compliance was noted for the Palmaz-Schatz, Strecker, and Wallstent designs. The Palmaz-Schatz and Strecker stents caused increased arterial wall rigidity, the Symphony and Wallstent designs had no effect, and the Memotherm and Cragg stents caused decreased wall rigidity. Stents made of stiff metal yielded different early results than did stents made of the less rigid nitinol.
CONCLUSION: Soon after implantation, the six stent designs elicited varying changes in blood flow, arterial compliance, and arterial wall mechanics. Contralateral arterial flow also was affected.
Index terms: Animals • Arteries, iliac, 984.1268 • Arteries, grafts and prostheses, 984.1268 • Interventional procedures, comparative studies, 984.1268 • Interventional procedures, experimental studies, 984.1268
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