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Quantification of Distention in CT Colonography: Development and Validation of Three Computer Algorithms¹

¹ From the Department of Radiology, Stanford University Medical Center, MC 5105, 300 Pasteur Dr, Stanford, CA 94305 (P.W.H., D.S.P., S.N., R.B.J., J.M., A.J., C.F.B.); Mayo Medical School, Rochester, Minn (P.W.H.); Department of Radiology, University of California San Francisco and San Francisco Veterans Administration Medical Center (J.Y., A.S.G.); and Department of Radiology, New York University Medical School, NY (A.J.). From the 2000 RSNA scientific assembly. Received March 14, 2001; revision requested April 18; revision received July 9; accepted August 2. Supported in part by National Institutes of Health grant RO1 CA72023 and an award from the Society of Computed Body Tomography and Magnetic Resonance. Address correspondence to C.F.B. (e-mail: beaulieu@stanford.edu).

Three bowel distention–measuring algorithms for use at computed tomographic (CT) colonography were developed, validated in phantoms, and applied to a human CT colonographic data set. The three algorithms are the cross-sectional area method, the moving spheres method, and the segmental volume method. Each algorithm effectively quantified distention, but accuracy varied between methods. Clinical feasibility was demonstrated. Depending on the desired spatial resolution and accuracy, each algorithm can quantitatively depict colonic diameter in CT colonography.

Index terms: Colon, CT, 75.12115 • Computers, diagnostic aid, 75.12115 • Computed tomography (CT), computer programs, 75.12115 • Computed tomography (CT), image processing, 75.12115 • Phantoms

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