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Published online before print June 13, 2002, 10.1148/radiol.2241011222
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(Radiology 2002;224:393-403.)
© RSNA, 2002


Gastrointestinal Imaging

Dietary Fecal Tagging as a Cleansing Method before CT Colonography: Initial Results—Polyp Detection and Patient Acceptance1

Philippe A. Lefere, MD, Stefaan S. Gryspeerdt, MD, Jef Dewyspelaere, MD, Marc Baekelandt, MD and Bartel G. Van Holsbeeck, MD

1 From the Departments of Radiology (P.A.L., S.S.G., M.B., B.G.V.H.) and Gastroenterology (J.D.), Stedelijk Ziekenhuis, Bruggesteenweg 90, 8800 Roeselare, Belgium. From the 2000 RSNA scientific assembly. Received July 23, 2001; revision requested August 27; revision received October 22; accepted December 10. Address correspondence to P.A.L. (e-mail: radiologie@skynet.be).

PURPOSE: To compare reduced colonic cleansing based on dietary fecal tagging (FT) with standard (non-FT) colonic cleansing with regard to patient acceptance, sensitivity, and specificity.

MATERIALS AND METHODS: In 50 patients (FT group), FT was performed by means of diet, magnesium citrate, and a barium suspension. In another 50 patients (non-FT group), preparation was based on polyethylene glycol administration. All patients underwent conventional colonoscopy after computed tomographic (CT) colonography. Sensitivity and specificity for polyp detection were calculated by using conventional colonography as the reference standard. At CT colonography, fecal residue was evaluated. Patients were interviewed to determine discomfort, side effects, sleep quality, final opinion on examination comfort, and whether they would be reluctant to undergo the same examination again.

RESULTS: FT left more fecal residue but improved differentiation from polyps (FT specificity, 88% [30 of 34 patients]; non-FT, 77% [23 of 30 patients]). Sensitivities were comparable: FT, 88% (14 of 16 patients); non-FT, 85% (17 of 20 patients). FT significantly reduced discomfort, side effects, and sleep disturbance, and resulted in an improved final opinion of how comfortable the examination was (P < .05). Although FT improved patient willingness to repeat the examination, this improvement was not statistically significant (P > .05).

CONCLUSION: FT offers the patient a well-tolerated preparation and improves specificity, with improved differentiation of polyps from residual stool.

© RSNA, 2002

Index terms: Colon, CT, 75.12115, 75.12117, 75.1283 • Colon neoplasms, 75.311, 75.32 • Colonoscopy, 75.12115, 75.12117, 75.1283




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