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1 From the Department of Radiology (A.M.H., M.O.P., M.F., H.I.) and Clinic for Radiation Therapy (J.N.), University of Vienna, AKH-Wien, 8F, Währinger Gürtel 18-20, A-1090 Vienna, Austria; Department for Digital Picture Analysis, University of Technology Graz, Austria (R.R.B.); and Lucas MRI Center, Stanford University School of Medicine, Palo Alto, Calif (R.B.). Received October 18, 2001; revision requested January 2, 2002; final revision received April 25; accepted April 30. Address correspondence to A.M.H. (e-mail: andreas.herneth@univie.ac.at).
The authors evaluated the apparent diffusion coefficient (ADC) in the assessment of vertebral metastases and acute vertebral compression fractures in 22 patients with known or suspected vertebral metastases. On the basis of significantly (P < .03) different ADCs, vertebral metastases (0.69 x 10-3 mm2/sec) and pathologic compression fractures (0.65 x 10-3 mm2/sec) can be safely distinguished from vertebral bodies (1.66 x 10-3 mm2/sec) and benign compression fractures (1.62 x 10-3 mm2/sec). Thus, the use of ADCs may increase the specificity of magnetic resonance imaging in these patients.
© RSNA, 2002
Index terms: Magnetic resonance (MR), diffusion study, 30.12144 • Magnetic resonance (MR), echo planar, 30.121416, 30.12144 • Spine, MR, 30.121416, 30.12144 • Spine, secondary neoplasms, 30.33
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