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Coronary Artery Imaging with Real-time Navigator Three-dimensional Turbo-Field-Echo MR Coronary Angiography: Initial Experience¹

¹ From the Departments of Radiology (J.B., S.D., R.B.) and Cardiology (J.P., F.E.R.), Gasthuisberg University Hospital, Leuven, Belgium; and Department of Radiology, Mayo Clinic, Jacksonville, Fla (R.K.). Received October 29, 2001; revision requested December 10; final revision received July 17, 2002; accepted August 13. Address correspondence to J.B., Department of Radiology, University Hospitals, Catholic University of Leuven, Herestraat 49, B-3000 Leuven, Belgium (e-mail: jan.bogaert@uz.kuleuven.ac.be).

PURPOSE: To examine the value of a commercially available three-dimensional (3D) real-time navigator magnetic resonance (MR) coronary angiographic examination for detection of significant coronary artery stenoses, with conventional coronary angiography as the standard of reference.

MATERIALS AND METHODS: Twenty-one patients underwent 3D navigator MR coronary angiography immediately before catheterization. Two observers independently graded image quality on a scale from 1 (unreadable) to 5 (excellent), quantified coronary artery visualization, and evaluated the presence of significant (ie, >50% narrowing) stenoses. statistics were used to assess interobserver agreement, and receiver operating characteristic (ROC) analysis was used to assess stenosis detection.

RESULTS: For two of 21 patients, MR coronary angiogram quality was insufficient for analysis (mean score < 2). For the remaining 19 patients, the mean image quality scores assigned by observers 1 and 2 were 3.3 ± 1.0 (SD) and 3.2 ± 0.9, respectively. A mean of 71% of all coronary artery segments were visible at MR coronary angiography, and there was 91% agreement between the observers ( = 0.78). Observers 1 and 2 detected significant stenoses (n = 29) at MR coronary angiography with sensitivities of 44.4% and 55.5%, respectively; specificities of 95.1% and 83.7%, respectively; and 80% agreement ( = 0.35). Areas under the ROC curve were 0.817 and 0.795 for observers 1 and 2, respectively.

CONCLUSION: Large portions of the coronary arteries can be visualized with MR coronary angiography. Imaging results are not consistently reliable, however. The examination is premature for routine clinical assessment of significant coronary artery stenosis owing to low sensitivity and large observer variability.

© RSNA, 2003

Index terms: Coronary angiography, 54.1242, 54.1244 • Coronary vessels, MR, 54.121412, 54.121416, 54.12142 • Coronary vessels, stenosis or obstruction, 54.76 • Magnetic resonance (MR), vascular studies, 54.121412, 54.121416, 54.12142

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