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1 From the Institute of Diagnostic Radiology, University Hospital Zurich, Switzerland (T.S., S.W., H.A., M.K., B.M., T.B.); and Institute of Radiology, Kantonsspital Chur, Spitäler Chur, Loestrasse 170, CH-7000 Chur, Switzerland (T.B.). Received November 2, 2004; revision requested January 1, 2005; revision received January 27; accepted February 25. Supported by the National Center of Competence and Research, Computer Aided and Image Guided Medical Interventions, of the Swiss National Science Foundation. Address correspondence to T.B. (e-mail: thomas_boehm{at}gmx.net).
Institutional review board approval and written informed consent from all patients were obtained. Diagnostic accuracy of three reconstructions of 16detector row computed tomographic (CT) angiography data with different section widths and increments (2.0 and 1.0 mm [CT data set 1], 1.0 and 0.5 mm [CT data set 2], and 0.75 and 0.4 mm [CT data set 3]) was compared with that of digital subtraction angiography (DSA) in 163 arterial segments in 17 patients with occlusive peripheral arterial disease (PAD). Arterial visibility was superior with CT as compared with DSA (P < .008). Sensitivity for stenosis detection did not differ between the CT reconstructions, whereas specificity was significantly improved when CT data set 3 was used (P < .017). Stenosis length did not differ significantly between CT angiography and DSA. Accuracy of stenosis detection was 88.2%, 90.8%, and 96.1% with CT data sets 1, 2, and 3, respectively. CT angiography has excellent diagnostic accuracy in the assessment of lower-leg PAD provided that the thinnest possible section width is used.
© RSNA, 2005
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