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Published online before print October 19, 2005, 10.1148/radiol.2373050234
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(Radiology 2005;237:1068-1074.)
© RSNA, 2005

Technical Developments

Radiofrequency Ablation of Metastatic Mediastinal Lymph Nodes during Cooling and Temperature Monitoring of the Tracheal Mucosa to Prevent Thermal Tracheal Damage: Initial Experience1

Takao Hiraki, MD, Kotaro Yasui, MD, Hidefumi Mimura, MD, Hideo Gobara, MD, Takashi Mukai, MD, Soichiro Hase, MD, Hiroyasu Fujiwara, MD, Nobuhisa Tajiri, MD, Yoshio Naomoto, MD, Tomoki Yamatsuji, MD, Yasuhiro Shirakawa, MD, Shinya Asami, MD, Hideki Nakatsuka, MD, Motohiko Hanazaki, MD, Kiyoshi Morita, MD, Noriaki Tanaka, MD and Susumu Kanazawa, MD

1 From the Departments of Radiology (T.H., K.Y., H.M., H.G., T.M., S.H., H.F., N. Tajiri, S.K.), Gastroenterological Surgery, Transplant, and Surgical Oncology (Y.N., T.Y., Y.S., S.A., N. Tanaka), and Anesthesiology and Resuscitology (H.N., M.H., K.M.), Okayama University Medical School, 2-5-1 Shikatacho, Okayama 700-8558, Japan. Received February 11, 2005; revision requested April 11; revision received April 19; accepted June 1. Address correspondence to T.H. (e-mail: takaoh{at}tc4.so-net.ne.jp).

Institutional review board approval and patient informed consent were obtained. Radiofrequency ablation in a total of 10 sessions was performed for each mediastinal lymph node metastasis from esophageal cancer that had a mean largest diameter of 2.2 cm ± 0.6 (standard deviation) in seven male patients (mean age, 59 years). During ablation, cooling and temperature of the tracheal mucosa were monitored in the proper position in eight of the 10 sessions; in the other two sessions, monitoring was not done because of tracheal stenosis (perforation resulted). Three of the four lymph nodes that were 2.0 cm or smaller in largest diameter showed no evidence of local progression for at least 1 year since ablation; all three of the nodes greater than 2.0 cm in largest diameter progressed within 6 months. The 1-year survival rate was 60%; the median survival time was 13 months. Radiofrequency ablation may be effective for local control of small metastatic mediastinal lymph nodes, and cooling and temperature monitoring of the tracheal mucosa in the proper position may prevent thermal tracheal damage.

© RSNA, 2005




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Current Status of Sonographically Guided Radiofrequency Ablation Techniques
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[Abstract] [Full Text] [PDF]


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