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Interstitial Lung Disease in Association with Polymyositis-Dermatomyositis: Long-term Follow-up CT Evaluation in Seven Patients

¹ Departments of Radiology (M.A.)
² Internal Medicine (H.H., M.S.), National Kinki Chuo Hospital for Chest Disease, 1180 Nagasone-cho, Sakai City, Osaka 591-8555, Japan.

View larger version (79K): [in a new window]   Figure 1a. Patient 2. Interstitial lung disease and associated polymyositis-dermatomyositis in a 61-year-old man. A, Initial CT scan of the lower part of the right lung shows patchy areas of consolidation (arrowheads) in the subpleural region. B, CT scan obtained at 1-year follow-up shows progression of the extent of the area of opacity despite corticosteroid therapy. Traction bronchiectasis (arrowheads) and small cystic lesions are seen within the area of ground-glass opacity. C, Final CT scan obtained at 2-year follow-up shows considerable improvement in the areas of ground-glass opacity and subpleural consolidation, but small cystic lesions (arrowheads) are present. D, Initial CT scan of the lower part of the left lung shows patchy areas of consolidation (arrowheads) in the subpleural region. E, Final CT scan of the lower part of the left lung obtained at 2-year follow-up shows honeycombing (arrowheads).

View larger version (78K): [in a new window]   Figure 1d. Patient 2. Interstitial lung disease and associated polymyositis-dermatomyositis in a 61-year-old man. A, Initial CT scan of the lower part of the right lung shows patchy areas of consolidation (arrowheads) in the subpleural region. B, CT scan obtained at 1-year follow-up shows progression of the extent of the area of opacity despite corticosteroid therapy. Traction bronchiectasis (arrowheads) and small cystic lesions are seen within the area of ground-glass opacity. C, Final CT scan obtained at 2-year follow-up shows considerable improvement in the areas of ground-glass opacity and subpleural consolidation, but small cystic lesions (arrowheads) are present. D, Initial CT scan of the lower part of the left lung shows patchy areas of consolidation (arrowheads) in the subpleural region. E, Final CT scan of the lower part of the left lung obtained at 2-year follow-up shows honeycombing (arrowheads).

View larger version (93K): [in a new window]   Figure 2a. Patient 3. Interstitial lung disease and associated polymyositis-dermatomyositis in a 60-year-old woman. (a) Initial CT scan shows subpleural consolidation (arrowheads). (b) CT scan obtained at 1-year follow-up shows considerable resolution of lesions after corticosteroid therapy. (c) Final CT scan obtained 2 years later during sudden, rapid deterioration shows extensive areas of ground-glass opacity (arrowheads) and consolidation.

View larger version (138K): [in a new window]   Figure 2b. Patient 3. Interstitial lung disease and associated polymyositis-dermatomyositis in a 60-year-old woman. (a) Initial CT scan shows subpleural consolidation (arrowheads). (b) CT scan obtained at 1-year follow-up shows considerable resolution of lesions after corticosteroid therapy. (c) Final CT scan obtained 2 years later during sudden, rapid deterioration shows extensive areas of ground-glass opacity (arrowheads) and consolidation.

View larger version (135K): [in a new window]   Figure 2c. Patient 3. Interstitial lung disease and associated polymyositis-dermatomyositis in a 60-year-old woman. (a) Initial CT scan shows subpleural consolidation (arrowheads). (b) CT scan obtained at 1-year follow-up shows considerable resolution of lesions after corticosteroid therapy. (c) Final CT scan obtained 2 years later during sudden, rapid deterioration shows extensive areas of ground-glass opacity (arrowheads) and consolidation.

View larger version (80K): [in a new window]   Figure 3. Patient 1. Interstitial lung disease and associated polymyositis-dermatomyositis in a 43-year-old man. A, Initial CT scan shows areas of linear and ground-glass opacity (arrowheads) in the subpleural region. B, CT scan obtained at 3-year follow-up shows progression of lesions (arrowheads). C, Final CT scan obtained at 8-year follow-up shows progression of honeycombing (arrowheads) toward the central part of the lung.

View larger version (137K): [in a new window]   Figure 4. Patient 4. Interstitial lung disease and associated polymyositis-dermatomyositis in a 48-year-old woman. CT scan shows patchy areas of consolidation (arrowheads) in both the central and the peripheral portions of the lungs.