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Subcutaneous Granuloma Annulare: MR Imaging Features in Six Children and Literature Review

Sunny Chung, MD1, Donald P. Frush, MD1, Neil S. Prose, MD2, Christopher R. Shea, MD2,3, Tal Laor, MD4 and George S. Bisset, MD1

1 Departments of Radiology, Division of Pediatric Radiology (S.C., D.P.F., G.S.B.)
2 Medicine, Division of Dermatology (N.S.P., C.R.S.)
3 Pathology, Division of Diagnostic Pathology (C.R.S.), Duke University Medical Center, Box 3808, Erwin Rd, Durham, NC 27710
4 Department of Radiology, Children's Hospital, Boston, Mass (T.L.).



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Figure 1. Photomicrograph of a histologic preparation of SGA. A mucinous central zone of amorphous, degenerated, connective tissue (C) is surrounded by a typical palisade of epithelioid and multinucleated histiocytes (arrow). (Hematoxylin-eosin stain; original magnification, x100.)

 


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Figure 2a. MR images in a 21/2-year-old girl with a painless prepatellar mass. (a) Sagittal T1-weighted image (500/9) shows a mass (arrows) localized to the subcutaneous tissue with signal intensity similar to that of skeletal muscle. A central component (C) of slightly lower signal intensity is present. (b) Sagittal fast spin-echo T2-weighted image (3,000/96 [effective]) obtained with fat saturation demonstrates that the mass (arrows) has predominantly high signal intensity with a more homogeneous high-signal-intensity central region (C).

 


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Figure 2b. MR images in a 21/2-year-old girl with a painless prepatellar mass. (a) Sagittal T1-weighted image (500/9) shows a mass (arrows) localized to the subcutaneous tissue with signal intensity similar to that of skeletal muscle. A central component (C) of slightly lower signal intensity is present. (b) Sagittal fast spin-echo T2-weighted image (3,000/96 [effective]) obtained with fat saturation demonstrates that the mass (arrows) has predominantly high signal intensity with a more homogeneous high-signal-intensity central region (C).

 


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Figure 3a. Axial MR images in a 3-year-old boy with a painless pretibial soft-tissue mass. (a) T1-weighted image (500/22) demonstrates an ill-defined subcutaneous mass (M) that does not extend deep to the fascia. (b) Fast spin-echo T2-weighted image (4,000/112 [effective]) obtained with fat saturation shows that the mass (M) has mixed but predominantly high-signal-intensity characteristics. (c) T1-weighted contrast-enhanced image (500/22) obtained with fat saturation shows homogeneous enhancement of the mass (M).

 


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Figure 3b. Axial MR images in a 3-year-old boy with a painless pretibial soft-tissue mass. (a) T1-weighted image (500/22) demonstrates an ill-defined subcutaneous mass (M) that does not extend deep to the fascia. (b) Fast spin-echo T2-weighted image (4,000/112 [effective]) obtained with fat saturation shows that the mass (M) has mixed but predominantly high-signal-intensity characteristics. (c) T1-weighted contrast-enhanced image (500/22) obtained with fat saturation shows homogeneous enhancement of the mass (M).

 


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Figure 3c. Axial MR images in a 3-year-old boy with a painless pretibial soft-tissue mass. (a) T1-weighted image (500/22) demonstrates an ill-defined subcutaneous mass (M) that does not extend deep to the fascia. (b) Fast spin-echo T2-weighted image (4,000/112 [effective]) obtained with fat saturation shows that the mass (M) has mixed but predominantly high-signal-intensity characteristics. (c) T1-weighted contrast-enhanced image (500/22) obtained with fat saturation shows homogeneous enhancement of the mass (M).

 





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