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Autosomal Dominant Polycystic Kidney Disease Types 1 and 2: Assessment of US Sensitivity for Diagnosis1

Carlos Nicolau, MD, Roser Torra, MD, PhD, Cèlia Badenas, PhD, Ramón Vilana, MD, PhD, Luis Bianchi, MD, PhD, Rosa Gilabert, MD, PhD, Alejandro Darnell, MD, PhD and Concepció Brú, MD, PhD

1 From the Ultrasound Unit, Department of Radiology (C.N., R.V., L.B., R.G., C. Brú), and the Departments of Nephrology (R.T., C. Badenas, A.D.) and Genetics (C. Badenas), Hospital Clínic, University of Barcelona, Villarroel 170, 08036 Barcelona, Spain. Received December 1, 1998; revision requested January 26, 1999; revision received February 18; accepted April 15. From the 1998 RSNA scientific assembly. Supported in part by a grant of the Fondo de Investigaciones Sanitarias de la Seguridad Social (FIS 97/2047). Address reprint requests to C.N. (e-mail: nicolau@medicina.ub.es).



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  		Figure 1. Longitudinal US images of the right kidney in a 28-year-old man with ADPKD type 1 show nephromegaly with multiple anechoic cysts. This is the most typical presentation of ADPKD in advanced stages.

 


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  		Figure 2. Longitudinal US image of the left kidney in a 26-year-old woman with ADPKD type 1 shows only one small cortical cyst (arrow). There were no cysts on the US image of the right kidney. The study was designated as indeterminate on the basis of the diagnostic criteria.

 




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