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Screening for Stroke in Sickle Cell Anemia: Comparison of Transcranial Doppler Imaging and Nonimaging US Techniques¹

¹ From the Department of Radiology, Children’s Health Care of Atlanta at Scottish Rite, 1001 Johnson Ferry Rd NE, Atlanta, GA 30342. Received February 27, 2001; revision requested April 2; final revision received September 14; accepted September 20. Funding for purchase of Nicolet Companion EME Transcranial Doppler machine was provided by the Children’s Health Care of Atlanta Foundation. Address correspondence to A.S.N. (e-mail: ariane.neish@choa.org).

View larger version (27K): [in a new window]   Figure 1. Bar graph shows comparison of velocity readings in centimeters per second obtained at nonimaging transcranial Doppler US with a Nicolet machine (black bars) and those obtained at transcranial Doppler US imaging with GE or Acuson machines (white bars). No significant differences in velocity measurements were found in the middle cerebral artery (MCA), distal internal carotid artery (ICA), or anterior cerebral artery (ACA). However, significant differences were identified in velocity readings in the bifurcation of the distal internal carotid artery (BIF), in the posterior cerebral artery (PCA), and in the basilar artery (BA). The values reported represent means of velocities of the data reported in Table 1.

View larger version (26K): [in a new window]   Figure 2. Bar graph shows comparison of RIs obtained at nonimaging transcranial Doppler US with a Nicolet machine (black bars) and those obtained at transcranial Doppler US imaging with GE or Acuson machines (white bars). The values reported represent means of RIs calculated from the data reported in Table 1. The graph depicts significant differences in RI measurements for every vessel. ACA = anterior cerebral artery, BA = basilar artery, BIF = bifurcation of the distal internal carotid artery, ICA = internal carotid artery, MCA = middle cerebral artery, PCA = posterior cerebral artery.