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Published online before print March 7, 2002, 10.1148/radiol.2232010775
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(Radiology 2002;223:331-337.)
© RSNA, 2002

Small Hepatocellular Carcinoma: Comparison of Radio-frequency Ablation and Percutaneous Microwave Coagulation Therapy1

Toshiya Shibata, MD, Yuji Iimuro, MD, Yuzo Yamamoto, MD, Yoji Maetani, MD, Fumie Ametani, MD, Kyo Itoh, MD and Junji Konishi, MD

1 From the Departments of Diagnostic Imaging and Nuclear Medicine (T.S., Y.M., F.A., K.I., J.K.) and Gastroenterological Surgery (Y.I., Y.Y.), Kyoto University Graduate School of Medicine, 54-Kawaharacho, Shogoin, Sakyoku, Kyoto 606-8507, Japan. Received April 16, 2001; revision requested May 11; revision received July 24; accepted September 7. Address correspondence to T.S. (e-mail: ksj@kuhp.kyoto-u.ac.jp).



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Figure 1a. A 2.2-cm-diameter HCC nodule in a 62-year-old man. (a) Transverse early-phase CT scan obtained before RF ablation shows an enhancing tumor (arrows) in the posterosuperior segment of the right lobe of the liver. (b) Right intercostal sonogram shows the expanded hook-shaped tines (arrowheads) of the RF ablation electrode that is introduced into the nodule with US guidance. (c) Transverse early-phase CT scan obtained 1 month after RF ablation shows no enhancement in the tumor area (arrows). (d) Right intercostal sonogram shows that during RF ablation the nodule became hyperechoic owing to vapor produced during treatment.

 


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Figure 1b. A 2.2-cm-diameter HCC nodule in a 62-year-old man. (a) Transverse early-phase CT scan obtained before RF ablation shows an enhancing tumor (arrows) in the posterosuperior segment of the right lobe of the liver. (b) Right intercostal sonogram shows the expanded hook-shaped tines (arrowheads) of the RF ablation electrode that is introduced into the nodule with US guidance. (c) Transverse early-phase CT scan obtained 1 month after RF ablation shows no enhancement in the tumor area (arrows). (d) Right intercostal sonogram shows that during RF ablation the nodule became hyperechoic owing to vapor produced during treatment.

 


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Figure 1c. A 2.2-cm-diameter HCC nodule in a 62-year-old man. (a) Transverse early-phase CT scan obtained before RF ablation shows an enhancing tumor (arrows) in the posterosuperior segment of the right lobe of the liver. (b) Right intercostal sonogram shows the expanded hook-shaped tines (arrowheads) of the RF ablation electrode that is introduced into the nodule with US guidance. (c) Transverse early-phase CT scan obtained 1 month after RF ablation shows no enhancement in the tumor area (arrows). (d) Right intercostal sonogram shows that during RF ablation the nodule became hyperechoic owing to vapor produced during treatment.

 


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Figure 1d. A 2.2-cm-diameter HCC nodule in a 62-year-old man. (a) Transverse early-phase CT scan obtained before RF ablation shows an enhancing tumor (arrows) in the posterosuperior segment of the right lobe of the liver. (b) Right intercostal sonogram shows the expanded hook-shaped tines (arrowheads) of the RF ablation electrode that is introduced into the nodule with US guidance. (c) Transverse early-phase CT scan obtained 1 month after RF ablation shows no enhancement in the tumor area (arrows). (d) Right intercostal sonogram shows that during RF ablation the nodule became hyperechoic owing to vapor produced during treatment.

 


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Figure 2a. A 3.0-cm-diameter HCC nodule near the right hepatic vein in a 69-year-old man. (a) Right intercostal sonogram shows the expanded tines (arrowheads) of the electrode that was used to perform RF ablation of a nodule in the posterosuperior segment of the right lobe of the liver. The tines are inside the nodule. (b) Transverse late-phase CT scan obtained after three RF ablation sessions shows residual enhancing lesions (arrows) in the nodule. Therapeutic effect was incomplete.

 


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Figure 2b. A 3.0-cm-diameter HCC nodule near the right hepatic vein in a 69-year-old man. (a) Right intercostal sonogram shows the expanded tines (arrowheads) of the electrode that was used to perform RF ablation of a nodule in the posterosuperior segment of the right lobe of the liver. The tines are inside the nodule. (b) Transverse late-phase CT scan obtained after three RF ablation sessions shows residual enhancing lesions (arrows) in the nodule. Therapeutic effect was incomplete.

 


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Figure 3a. A 2.0-cm-diameter HCC nodule in a 52-year-old woman. (a) Transverse early-phase CT scan obtained before PMC shows an enhancing nodule (arrowheads) in the posteroinferior segment of the right lobe of the liver. (b) Transverse early-phase CT scan obtained 18 months after PMC shows a nonenhancing area (arrows) at the site of the treated nodule. Therapeutic effect was complete, and no local recurrence was noted.

 


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Figure 3b. A 2.0-cm-diameter HCC nodule in a 52-year-old woman. (a) Transverse early-phase CT scan obtained before PMC shows an enhancing nodule (arrowheads) in the posteroinferior segment of the right lobe of the liver. (b) Transverse early-phase CT scan obtained 18 months after PMC shows a nonenhancing area (arrows) at the site of the treated nodule. Therapeutic effect was complete, and no local recurrence was noted.

 


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Figure 4. Graph illustrates comparison of the local recurrence rate between the RF ablation (RFA) and PMC (pMCT) groups (P = .20, log-rank test).

 





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