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Published online before print November 13, 2002, 10.1148/radiol.2261011275
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Artificial Thorax for MR Imaging Studies in Porcine Heart-Lung Preparations1

Jürgen Biederer, MD and Martin Heller, MD

1 From the Department of Diagnostic Radiology, University Hospital Kiel, Arnold-Heller-Strasse 9, 24105 Kiel 1, Germany. Received July 26, 2001; revision requested September 12; revision received February 8, 2002; accepted February 28. Address correspondence to J.B. (e-mail: juergen.biederer@rad.uni-kiel.de).



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  		Figure 1. Top view of lower shell of the artificial thorax (1) and artificial diaphragm (2) with deflated heart-lung preparation in situ. Tracheal tube (3) and balloon catheters (4) for a perfusion experiment are inserted.

 


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  		Figure 2. Lateral view of an inflated lung (*) within the closed and evacuated artificial thorax.

 


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  		Figure 3. Radiograph of a porcine heart-lung preparation inside the artificial thorax at 80 kVp and 3 mAs (small focus, antiscattering grid, film-focus distance of 110 cm). A round opacity on the right side resulted from implanted muscle fragment simulating a nodule (arrow).

 


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  		Figure 4. CT topogram (top) and transverse spiral CT scan (bottom) of a porcine lung inside the artificial thorax (beam collimation, 10 mm; table speed, 15 mm/sec; rotation time, 1 second; pitch factor, 1.5; 210 mAs; 137 kVp; reconstruction increment, 8 mm).

 


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  		Figure 5. Porcine heart-lung preparation within the artificial thorax. Digitally subtracted angiogram of the pulmonary arteries (slow circulation, perfusion with 200 mL/min of 0.9% NaCl solution, 10 mL of nonionic contrast material with an iodine content of 300 mg/mL) shows partially thrombosed segmental and subsegmental arteries (arrows).

 


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  		Figure 6. T2-weighted MR images of a porcine lung within the artificial thorax in a perfusion experiment with 200 mL/min of 0.9% NaCl. Top: Coronal RARE image (2,000/43, 350-mm field of view, 240 x 256 matrix, 7-mm section) shows atelectasis of the right upper lobe (arrow) after occlusion of the tracheal bronchus with the tube cuff. Bottom: Transverse fast spin-echo image (5,000/120, 350-mm field of view, 270 x 512 matrix, 8-mm section) shows marked edema (arrowheads) of the dependent segments after 1 hour of continuous perfusion.

 




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