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DOI: 10.1148/radiol.2261020517
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1H MR Spectroscopy in the Evaluation of the Severity of Chronic Liver Disease

Adrian K. P. Lim, FRCR, Gavin Hamilton, PhD, Nayna Patel, MSc, Jimmy D. Bell, PhD and Simon D. Taylor-Robinson, MD, FRCP

Robert Steiner MRI Unit, Imaging Sciences Department, Clinical Sciences Centre, Faculty of Medicine, Imperial College, Hammersmith Hospital Campus, Du Cane Road, London W12 0HS, England, e-mail: a.lim@ic.ac.uk



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Figure 1. Water-saturated 1H MR spectrum from a normal liver with a point-resolved spatially localized spectroscopic sequence (1,500/40 [repetition time msec/echo time msec]). Three lipid peaks are due to CH, CH2, and CH3 resonances, and a choline peak is due to choline (Cho) resonance. Peak X is unassigned. PPM = parts per million.

 


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Figure 2. Normal hepatic 31P MR spectrum illustrates phosphomonoester (PME), phosphodiester (PDE), inorganic phosphate (Pi), and {gamma}, {alpha}, ß nucleotide triphosphate (NTP) resonances. The spectrum is localized with an image-selected in vivo spectroscopic sequence (10,000/2). The broad component consisting of signals from motion-restricted phospholipid is indicated by the dotted line. PPM = parts per million.

 





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