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Estimated Radiation Risks Potentially Associated with Full-Body CT Screening¹

¹ From the Center for Radiological Research, Columbia University, 630 W 168th St, New York, NY 10032. Received July 11, 2003; revision requested September 30; final revision received January 22, 2004; accepted February 23. Supported by U.S. Department of Energy Low-Dose Radiation Research Program grants DE-FG-02–01ER6326 and DE-FG-02–98ER62686 and by National Institutes of Health grants EB002033 and CA 49062. Address correspondence to D.J.B. (e-mail: djb3@columbia.edu).

View larger version (25K): [in a new window]   Figure 1. Graph shows estimated excess relative risk () (±1 standard error [error bars]) of mortality (1950-1997) from solid cancer among groups of survivors in the life-span study cohort of atomic bomb survivors who were exposed to low doses (<500 mSv) of radiation (10). Dose limits for each group are shown above each data point. Dashed line represents result of zero-intercept linear fit (10) to all life-span study data from 5 to 4,000 mSv (higher dose points not shown). Arrows refer to estimated effective doses from one and five full-body CT examinations.

View larger version (32K): [in a new window]   Figure 2. Graph shows estimated excess cancer mortality risk according to age at time of exposure in a stationary population, with U.S. mortality risk rates, that is exposed to a radiation dose of 10 mSv (14). Data are averages between the sexes.

View larger version (31K): [in a new window]   Figure 3. Graph shows excess cancer mortality risks estimated to be associated with radiation from a single full-body CT examination at a given age. Estimated 95% credibility limits are approximately a factor of 3.2 in either direction.

View larger version (33K): [in a new window]   Figure 4. Graph shows excess cancer mortality risks estimated to be associated with radiation from annual full-body CT examinations. Annual examinations are assumed to commence at the specified age and continue until age 75.