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DOI: 10.1148/radiol.2342040013
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Chronic Obstructive Pulmonary Disease: Thin-Section CT Measurement of Airway Wall Thickness and Lung Attenuation1

Ilaria Orlandi, MD, Chiara Moroni, MD, Gianna Camiciottoli, MD, Maurizio Bartolucci, MD, Massimo Pistolesi, MD, Natale Villari, MD and Mario Mascalchi, MD, PhD

1 From the Radiodiagnostic Section, Department of Clinical Physiopathology (I.O., C.M., M.B., N.V., M.M.), and Respiratory Medicine Unit, Department of Critical Care (G.C., M.P.), University of Florence, Viale Morgagni 85, Florence 50134, Italy. Received January 13, 2004; revision requested March 16; revision received March 31; accepted May 17. Address correspondence to M.M. (e-mail: m.mascalchi@dfc.unifi.it).



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  		Figure 1. Schematic drawing of airway measurements. The formulas used to calculate the TDR and the PWA on the basis of wall thickness (T), bronchial external diameter (D), and bronchial lumen diameter (L) are as follows: TDR = T/D and {r05fe27e01} where {pi}(D/2)2 is the total area and {pi}(L/2)2 is the endoluminal area. B = bronchial wall area.

 


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  		Figure 2a. Bland and Altman plots show substantial agreement between the (a) PWA and (b) TDR values calculated from gated thin-section CT findings and the corresponding values calculated from nongated thin-section CT findings in 10 patients with COPD. Lines above and below averages line illustrate the 95% confidence interval.

 


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  		Figure 2b. Bland and Altman plots show substantial agreement between the (a) PWA and (b) TDR values calculated from gated thin-section CT findings and the corresponding values calculated from nongated thin-section CT findings in 10 patients with COPD. Lines above and below averages line illustrate the 95% confidence interval.

 




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