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Published online before print January 19, 2006, 10.1148/radiol.2383041769
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Abdominal and Iliac Arterial Stenoses: Comparative Double-blinded Randomized Study of Diagnostic Accuracy of 3D MR Angiography with Gadodiamide or Gadopentetate Dimeglumine1

Philipp J. Schaefer, MD, Frank P. Boudghene, MD, Hans J. Brambs, MD, Montserrat Bret-Zurita, MD, Jose L. Caniego, MD, Richard A. Coulden, MD, Hans B. Gehl, MD, Renate Hammerstingl, MD, Armin Huber, MD, Ramiro J. Mendez, MD, Michel Nonent, MD, Joerg W. Oestmann, MD, Jesus C. Pueyo, MD, PhD, Siegfried Thurnher, MD, Dominik Weishaupt, MD and Thomas Jahnke, MD

1 From the Department of Diagnostic Radiology, University Hospital of Schleswig-Holstein Campus Kiel, Arnold-Heller-Strasse 9, 24105 Kiel, Germany (P.J.S.). A complete list of centers that participated in this study and author affiliations appears in the Acknowledgment at the end of this article. Received October 14, 2004; revision requested December 22; revision received January 27, 2005; accepted February 28; final version accepted May 11. Supported by a grant from Amersham Health. Address correspondence to P.J.S. (e-mail: jp.schaefer{at}rad.uni-kiel.de).


Figure 1
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  		Figure 1: Flow diagram of study population. The term "trade product" refers to the power injector filled with gadopentetate rather than gadodiamide.

 

Figure 2
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  		Figure 2a: Bilateral renal artery stenosis in 69-year-old man. Anteroposterior projections of (a) intraarterial DSA image and (b) coronal gadopentetate-enhanced maximum intensity projection obtained with 3D fast low-angle shot 1.5-T MR imaging (4.6/1.8; matrix, 200 [frequency]x 512 [phase]; flip angle, 30°; field of view, 420 mm; acquisition time, 23 seconds) and phased-array coil reveal clearly relevant (≥50%) stenoses in right and left renal arteries (arrows) and stenoses less than 50% in infrarenal aorta and left common iliac artery.

 

Figure 2
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  		Figure 2b: Bilateral renal artery stenosis in 69-year-old man. Anteroposterior projections of (a) intraarterial DSA image and (b) coronal gadopentetate-enhanced maximum intensity projection obtained with 3D fast low-angle shot 1.5-T MR imaging (4.6/1.8; matrix, 200 [frequency]x 512 [phase]; flip angle, 30°; field of view, 420 mm; acquisition time, 23 seconds) and phased-array coil reveal clearly relevant (≥50%) stenoses in right and left renal arteries (arrows) and stenoses less than 50% in infrarenal aorta and left common iliac artery.

 

Figure 3
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  		Figure 3a: Multiple stenoses in 58-year-old woman. (a) Left anterior oblique and (b) right anterior oblique intraarterial DSA projections reveal eccentric plaque (<50%) in left common iliac artery (arrow) and nonrelevant (<50%) stenoses in both external iliac arteries. Coronal gadodiamide-enhanced (c) anteroposterior and (d) left anterior oblique projections obtained with 3D 1.5-T fast low-angle shot MR imaging (4.6/1.8; matrix, 200 [frequency]x 512 [phase]; flip angle, 30°; field of view, 420 mm; acquisition time, 23 seconds) and phased-array coil show relevant (≥50%) stenosis in left common iliac artery (arrow), nonrelevant (<50%) stenosis in left external iliac artery, and subtotal occlusion in right external iliac artery.

 

Figure 3
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  		Figure 3b: Multiple stenoses in 58-year-old woman. (a) Left anterior oblique and (b) right anterior oblique intraarterial DSA projections reveal eccentric plaque (<50%) in left common iliac artery (arrow) and nonrelevant (<50%) stenoses in both external iliac arteries. Coronal gadodiamide-enhanced (c) anteroposterior and (d) left anterior oblique projections obtained with 3D 1.5-T fast low-angle shot MR imaging (4.6/1.8; matrix, 200 [frequency]x 512 [phase]; flip angle, 30°; field of view, 420 mm; acquisition time, 23 seconds) and phased-array coil show relevant (≥50%) stenosis in left common iliac artery (arrow), nonrelevant (<50%) stenosis in left external iliac artery, and subtotal occlusion in right external iliac artery.

 

Figure 3
View larger version (85K):

[in a new window]
  		Figure 3c: Multiple stenoses in 58-year-old woman. (a) Left anterior oblique and (b) right anterior oblique intraarterial DSA projections reveal eccentric plaque (<50%) in left common iliac artery (arrow) and nonrelevant (<50%) stenoses in both external iliac arteries. Coronal gadodiamide-enhanced (c) anteroposterior and (d) left anterior oblique projections obtained with 3D 1.5-T fast low-angle shot MR imaging (4.6/1.8; matrix, 200 [frequency]x 512 [phase]; flip angle, 30°; field of view, 420 mm; acquisition time, 23 seconds) and phased-array coil show relevant (≥50%) stenosis in left common iliac artery (arrow), nonrelevant (<50%) stenosis in left external iliac artery, and subtotal occlusion in right external iliac artery.

 

Figure 3
View larger version (102K):

[in a new window]
  		Figure 3d: Multiple stenoses in 58-year-old woman. (a) Left anterior oblique and (b) right anterior oblique intraarterial DSA projections reveal eccentric plaque (<50%) in left common iliac artery (arrow) and nonrelevant (<50%) stenoses in both external iliac arteries. Coronal gadodiamide-enhanced (c) anteroposterior and (d) left anterior oblique projections obtained with 3D 1.5-T fast low-angle shot MR imaging (4.6/1.8; matrix, 200 [frequency]x 512 [phase]; flip angle, 30°; field of view, 420 mm; acquisition time, 23 seconds) and phased-array coil show relevant (≥50%) stenosis in left common iliac artery (arrow), nonrelevant (<50%) stenosis in left external iliac artery, and subtotal occlusion in right external iliac artery.

 




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