Radiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

DOI: 10.1148/radiol.2393050418
This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Shi, R.
Right arrow Articles by Beaulieu, C. F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shi, R.
Right arrow Articles by Beaulieu, C. F.

CT Colonography: Influence of 3D Viewing and Polyp Candidate Features on Interpretation with Computer-aided Detection1

Rong Shi, MD, Pamela Schraedley-Desmond, PhD, Sandy Napel, PhD, Eric W. Olcott, MD, R. Brooke Jeffrey, Jr, MD, Judy Yee, MD, Michael E. Zalis, MD, Daniel Margolis, MD, David S. Paik, PhD, Anthony J. Sherbondy, MS, Padmavathi Sundaram, MS and Christopher F. Beaulieu, MD, PhD

1 From the Department of Radiology, Stanford University Medical Center, James H. Clark Center, 318 Campus Dr, Room S324, Stanford, CA 94305-5450 (R.S., P. Schraedley-Desmond, S.N., E.W.O., R.B.J., D.M., D.S.P., A.J.S., P. Sundaram, C.F.B.); Veterans Affairs Palo Alto Health Care System, Palo Alto, Calif (E.W.O.); Department of Radiology, University of California, San Francisco, San Francisco, Calif (J.Y.); San Francisco Veterans Affairs Medical Center, San Francisco, Calif (J.Y.); and Department of Radiology, Massachusetts General Hospital, Boston, Mass (M.E.Z.). Received March 11, 2005; revision requested May 4; revision received May 20; accepted June 20; final version accepted August 24. Supported by the National Institutes of Health (R01 CA72023 and 1 U54 GM072970) and the Lucas Foundation. Address correspondence to R.S. (e-mail: rshi{at}stanford.edu).


Figure 1
View larger version (84K):

[in a new window]
  		Figure 1: Magnified, A, transverse, and, B, coronal SURF interface sections show an experimental polyp, which was confirmed with colonoscopy, in the center of the bounding box. C, Volume-rendering window, which was enabled during reference standard setting and combined 2D and 3D reading and disabled during 2D reading, shows a subvolume surrounding the polyp candidate. The polyp (arrow) and haustral fold (arrowheads) were added. D, Polyp CAD manager used to establish the reference standard in the blinded reader trial.

 

Figure 2
View larger version (63K):

[in a new window]
  		Figure 2: Polyp CAD manager window used with SURF. The left panel lists polyp candidates presented to each reader. During reference standard setting, all panels were used to characterize TP and FP polyp candidates, assign a confidence level, and rate each feature according to parameters shown. During blinded reader review, only the subpanel (indicated by the dashed box) was used to enter confidence levels for 2D or combined 2D and 3D viewing (ie, study readers were blinded to information concerning additional features and optical colonoscopy results).

 

Figure 3
View larger version (37K):

[in a new window]
  		Figure 3: Receiver operating characteristic curves for individual radiologists and lesions of all sizes. For readers 1, 3, and 4, there was a significant increase in the Az value with combined 2D and 3D viewing (2D3D) during interpretation. Reader 2 demonstrated extremely good performance with 2D viewing alone; thus, the addition of 3D viewing was not associated with a significant increase in the Az value.

 




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
RADIOLOGY RADIOGRAPHICS RSNA JOURNALS ONLINE
Copyright © 2006 by the Radiological Society of North America.