Morphologic Phenotyping with MR Microscopy: The Visible Mouse

This supplement demonstrates additional views of the 3D MR images of the normal mouse shown in Figures 3 and 4 of the article.

The subject is a 60-day-old male C57BL/6J mouse weighing 28 g. The specimen preparation and staining protocol are described in the article. A pair of mouse browsers is available at http://wwwcivm.mc.duke.edu/Radiology/index.html for interactively selecting views of the 3D acquisitions (Fig E1). Several representative images from the 3D sets are shown here:

Images covering the entire mouse (Fig E2)
Higher-resolution images of the same mouse covering only the midabdomen (Fig E3)

Figure E1. The interactive viewers available at http://wwwcivm.mc.duke.edu/Radiology/index.html for the whole mouse and midabdomen provide an overview of the two imaging volumes by sectioning them at increments in three planes.


Figure E2. Selected transverse (A), coronal (B), and sagittal (C) views from a 3D MR acquisition of the whole mouse. Click on the images to display the full-resolution versions (50/5.12, 1024 x 256 x 256 array, 110-µm isotropic voxel, 16 signals acquired).


Figure E3. The midabdomen of the same mouse as in Figures E1 and E2. Selected transverse (A), coronal (B), and sagittal (C) views from a 3D MR acquisition. Click on the images to display the full-resolution versions (50/5.12, 512 x 512 x 512 array, 50-µm isotropic voxel, four signals acquired).

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